How gas chromatography can optimise your cellulose type assays

Cellulose assays that utilise capillary and packed column gas chromatography reduce the risk of out-of-specification results, while also improving the accuracy and quality of the data generated.

At Butterworth Laboratories, gas chromatography (GC) is used for accurate cellulose assays of substances like hypromellose and methylcellulose. The method, aligned with pharmacopoeial standards (USP, PhEur, JP, ChP), provides reliable testing and improved precision for clients.

While capillary columns offer sharper chromatographic results, the packed column method has historically shown better repeatability for certain analytes like methyl iodide. To mitigate risks, BLL has set stricter %RSD limits of NMT 1.0%, ensuring more reliable data and minimising the likelihood of out-of-specification (OOS) results.

To read this white paper, click HERE.