For over 40 years, Butterworth Laboratories has provided independent, contract analytical services to the global pharmaceutical and related industries.
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Butterworth explores the history of drug regulation harmonisation and what more needs to be done in an article produced in collaboration with Pharmaceutical Technology. Establishing the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) marked a significant milestone in the global regulation of pharmaceuticals. Originating from a 1990 meeting in […]
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With World Mental Health Day falling on 10 October 2024, Butterworth Laboratories is embracing the entire month of October as an opportunity to raise awareness and promote well-being among our staff. We understand the importance of mental health and want to ensure all staff feel supported, heard, and equipped with the tools to manage their well-being. Throughout […]
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High-performance liquid chromatography can highlight the presence of 16 free amino acids in a sample better than its thin-layer chromatography counterpart. For decades, the determination of ninhydrin-positive substances (NPS) in amino acids relied on thin-layer chromatography (TLC). However, since 2013, high-performance liquid chromatography (HPLC) has progressively replaced TLC in the European Pharmacopoeia due to its […]
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Following a successful trial last term, Butterworth Labs is set to extend its partnership with Kingston University. Starting in October 2024, students pursuing Chemistry and Pharmaceutical-related degrees will be welcomed to Butterworth Labs’ Teddington site. During their visit, students will participate in a presentation about the lab’s work, take a guided tour of the facilities, […]
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Cellulose assays that utilise capillary and packed column gas chromatography reduce the risk of out-of-specification results, while also improving the accuracy and quality of the data generated. At Butterworth Laboratories, gas chromatography (GC) is used for accurate cellulose assays of substances like hypromellose and methylcellulose. The method, aligned with pharmacopoeial standards (USP, PhEur, JP, ChP), […]
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2024 marks an important year for Butterworth Laboratories as this year we celebrate our 50th Anniversary. Since 1974, we have grown from a small local business, trading as The Butterworth Microanalytical Consultancy Ltd, into a leading provider of contract analytical chemistry testing. We serve clients around the world with our know-how and exceptional service, becoming known as […]
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Excipients play a fundamental role in API delivery, and John Welch, Butterworth’s Associate Director of Business Operations, believes that their testing is key to ensuring the safety of pharmaceutical products In the pharmaceutical industry, excipients can make up as much as 90% of a drug product, meaning their quality and safety are just as crucial […]
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As helium supplies face pressure, alternative solutions and regulatory changes drive industry adaptation. Helium, the second most abundant element in the universe after hydrogen, is produced in stars through nuclear fusion. However, on Earth, helium is relatively scarce. It is primarily generated by the underground radioactive decay of uranium (238 U). Over time, this helium […]
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Butterworth Laboratories’ latest article, published on the Pharmaceutical Technology website, explains why the latest guideline is significant in analytical procedure development for pharmaceuticals. To read the article, click here
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At Butterworth Laboratories, we prioritise our employees’ mental health and well-being. As such, we are happy to support Mental Health Awareness Week. As a company, we’ve established a dedicated program to train mental health first aiders who can provide support to individuals facing mental health challenges. Currently, we have 7 members of staff who have […]
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Our impression and speaking with other exhibitors, it felt as though the number of delegates attending was greater than has been the case since the Pandemic etc. As usual it was good to meet up with clients, regular exhibitors, competitors and old friends and colleagues. Frank Judge, our Consultant Chemist – Chromatography made his presentation […]
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THE DETERMINATION OF NINHYDRIN-POSITIVE SUBSTANCES IN PhEur AMINO ACIDS Our Projects department has now successfully verified 15 out of the 21 amino acids listed in Free Amino Acid Monographs using our Hitachi high-speed Amino Acid analyser. This work will continue until all 21 amino acids have been verified and we’ll keep you posted on our […]
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Come and join us at the JPAG Meeting being held at the Royal Society of Chemistry, Burlington House, London at the JPAG Meeting on 21st March 2024. Raw materials, APIs and excipients play an important role in the manufacturing of pharmaceutical products therefore it is important to assess and monitor quality of these materials throughout […]
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The decades-old test for ninhydrin-positive substances in individual amino acid monographs was scrapped in 2013. But is the current approach satisfactory? Butterworth Laboratories takes a deep dive into the evolving landscape of amino acid testing. The general challenge posed by the analysis of free amino acids is that many degrade under the high sample injector […]
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To celebrate the 50th Anniversary of Butterworth Laboratories Limited, founded in 1974 by Doris Butterworth to perform Elemental Microanalysis, a new logo has been produced for 2024. We aim to have a number of initiatives to mark the anniversary as the year progresses.
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The latest technology combined with our expert team of scientists make us leaders in Quality Control Testing, Method Development, Method Validation and Stability Testing of both pharmaceutical raw materials and finished products.
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